Careful observation, precise language, and a fascination with what poet and science writer Alison Hawthorne Deming calls “the unknown” are some of the commonalities between poetry and science. This panel examines the ways in which the two disciplines inform and inspire each other. How can astronomy, geology, or biology illuminate a relationship or expose human truth in poetry? How does a fact become a metaphor when it crosses the science/poetry border? How do curiosity and imagination play out in both arenas? Using their own poetry as well as examples from other poets and scientists, Heather Hughes, Rosemary Starace, and Ellen Goldstein discuss how science figures in their search for poetic meaning and “the unknown.”